Priemel Yards, von Domarus C, Klatte In order to mais aussi al

Priemel Yards, von Domarus C, Klatte In order to mais aussi al

Bones mineralization faults and you can nutritional D insufficiency: histomorphometric investigation from iliac crest bone biopsies and you may circulating twenty-five-hydroxyvitamin D for the 675 patients. J Bones Miner Res 2010; 25: 305–312.

Zhou Y, Zhao LJ, Xu X et al. DNA methylation amounts of CYP2R1 and you will CYP24A1 expect supplement D reaction variation. J Steroid Biochem Mol Biol 2014; 144: 207–214.

Ralston SH, Binkley N, Boonen S et al. Randomized demo away from alendronate in addition to nutritional D3 rather than fundamental care and attention inside the osteoporotic postmenopausal ladies with supplement D insufficiency. Calcif Tissue Int 2011; 88: 485–494.

Weber K, Kaschig C, Erben RG . step 1 Alpha-hydroxyvitamin D2 and step one leader-hydroxyvitamin D3 enjoys anabolic consequences into cortical bone, but create intracortical renovations at the dangerous dosage in the ovariectomized mice. Bone 2004; 35: 704–710.

Li Yards, Healy DR, Simmons HA et al. Alfacalcidol regulates cancellous limbs inside ovariectomized mice. J Musculoskelet Neuronal Interact 2003; 3: 39–46.

Cures which have elage, and collagen crosslinks during the primate bone

Orimo H, Shiraki Yards, Hayashi Y mais aussi al. Outcomes of step 1 alpha-hydroxyvitamin D3 towards the lumbar bone mineral density and you can vertebral breaks in people which have postmenopausal weakening of bones. Calcif Tissue Int 1994; 54: 370–376.

Shikari Kushida Yards, Yamazaki K, Nagai K mais aussi al. H. Effects of 2 years’ treatment of weakening of bones with step 1 alpha-hydroxy vitamin D3 toward bones nutrient density and you will incidence out-of break: a placebo-managed, double-blind prospective study. Endocr J 1996; 43: 211–220.

Nuti R, Bianchi Grams, Brandi ML et al. Excellence off alfacalcidol compared to supplement D along with calcium supplements into the lumbar bone nutrient thickness during the postmenopausal osteoporosis. Rheumatol Int 2006; 26: 445–453.

Kubodera Letter, Tsuji Letter, Uchiyama Y mais aussi al. An alternate active vitamin D analogue, ED-71, grounds increase in bone size which have preferential consequences toward bone from inside the osteoporotic patients. J Telephone Biochem 2003; 88: 286–289.

Abe M, Tsuji Letter, Takahashi F mais aussi al. Summary of the medical pharmacokinetics from elin D3 by-product. Jpn Pharmacol Ther 2011; 39: 261–274.

Ritter CS, Brown AJ . Suppression out of PTH from the vitamin D analogue eldecalcitol is modulated of the its highest attraction toward solution vitamin D-joining protein and effectiveness k-calorie burning. J Cell Biochem 2011; 112: 1348–1352.

Kondo S, Takano T, Ono Y et al. Eldecalcitol minimizes osteoporotic splits of the book systems. J Steroid Biochem Mol Biol 2015; 148: 232–238.

Harada S, Mizoguchi T, Kobayashi Y et al. Each day government off elin D analog, develops limbs mineral thickness of the suppressing RANKL expression inside mouse trabecular bones. J Bone Miner Res 2012; 27: 461–473.

Hayashi Y, Fujita T, Inoue T

Matsumoto T, Ito M, Hayashi Y mais aussi al. A special effective vitamin D3 analogue, eldecalcitol, inhibits the risk of osteoporotic splits–a beneficial randomized, active comparator, double-blind study. Bones 2011; 49: 605–612.

Matsumoto T, Takano T, Saito H ainsi que al. Vitamin D analogs and bones: preclinical and you can scientific studies which have el; 3: 513.

Sakai A good, Ito M, Tomomitsu T ainsi que al. Effectiveness out of combined cures with alendronate (ALN) and you visit here will elin D analog, to that particular away from concomitant ALN, supplement D including calcium medication from inside the Japanese patients having pri; 26: 1193–1202.

Plum La, Fitzpatrick La, Ma X mais aussi al. 2MD, a special anabolic agent getting osteoporosis medication. Osteoporos Int 2006; 17: 704–715.

Ke HZ, Qi H, Crawford DT et al. A different supplement D analog, 2MD, regulates trabecular and cortical limbs mass and fuel during the ovariectomized mice having dependent osteopenia. J Limbs Miner Res 2005; 20: 1742–1755.

DeLuca HF, Bedale W, Binkley N mais aussi al. New vitamin D analogue 2MD grows bones turnover although not BMD when you look at the postmenopausal female which have osteopenia: results of a-1-seasons stage 2 double-blind, placebo-regulated, randomized clinical test. J Bone Miner Res 2011; 26: 538–545.